Although Rosenberg goes further than most experts in criticizing the FBI's anthrax investigation, her analysis of the case has become must reading for scientists and congressional staffers concerned about biodefense issues. (An FBI spokesman contacted by phone Thursday says the agency, too, is reading her work, but won't comment on it.) A microbiologist by training, Rosenberg worked as a cancer researcher at Memorial Sloan-Kettering Cancer Center, and as a professor of biochemistry at Cornell Medical College. A decade ago, she founded the Federation of American Scientists' biological and chemical weapons program, which she now heads.

In her analysis of the details known about the anthrax attacks to date, she has built a persuasive and disturbing case that the anthrax culprit is a deep insider to the U.S. government's biological weapons program.

Her conclusion is based on a collection of facts that point to a smaller and smaller number of individuals who could have met all the criteria for producing, handling and sending out the anthrax letters. The perpetrator seemed to have advanced expertise and experience in biological weapons like anthrax, for instance, and access to the technology to produce and refine it. He or she (but most think it's a he) probably would have had to have access to the anthrax vaccine, which is not widely available, in order not to succumb to the disease himself -- which means records of anthrax vaccinations, which require a yearly booster shot, would be available to further help identify the person.

In addition, the perpetrator used a highly sophisticated, lethal powder form of the Ames strain of anthrax. Although the strain itself came into the possession of USAMRIID in 1981, and was distributed from there for research purposes to about 20 labs, only about four facilities in the U.S. are believed to have the capability for "weaponizing" dry anthrax -- which basically means refining or cultivating a pure sample whose spores are so tiny and uniform they can easily be inhaled into the lungs.

Even the FBI seems to acknowledge the anthrax suspect has technical expertise in biology. In the letter sent to the 40,000 members of the American Society for Microbiology, Van Harp, assistant director of the FBI's Washington field office, told recipients: "It is very likely that one or more of you know this individual. A review of the information to date in this matter leads investigators to believe that a single person is most likely responsible for these mailings. This person is experienced working in a laboratory. Based on his or her selection of the Ames strain of Bacillus anthracis, one would expect that this individual has or had legitimate access to select biological agents at some time.

"This person has the technical knowledge and/or expertise to produce a highly refined and deadly product," the letter continued. "This person has exhibited a clear, rational thought process and appears to be very organized in the production and mailing of these letters. The perpetrator might be described as 'stand-offish' and likely prefers to work in isolation as opposed to a group/team setting. It is possible this person used off-hours in a laboratory or may have even established an improvised or concealed facility comprised of sufficient equipment to produce the anthrax."

Rosenberg says the perpetrator has dangled plenty of clues in front of investigators. One of those clues, she says, is a letter sent to the military police at the Quantico, Va., Marine base (and forwarded to the FBI) in late September -- well before the public was aware that anthrax was being sent in the mail -- that tried to frame a former U.S. biowarfare researcher as a bioterrorist. That anonymous letter stated that the writer had worked with the man, Dr. Ayaad Assaad, and had details about him that only an insider would know (although some details in the letter turned out to be incorrect.) The FBI has cleared Assaad of any possible connection to the case, but Assaad himself has criticized the agency for not zeroing in on his accuser as a likely culprit, since that person seemed to have foreknowledge about the anthrax attacks.

"The perpetrator has left multiple, blatant clues, seemingly on purpose," Rosenberg writes. "Second letters, addressed similarly to the anthrax letters and containing [talc] powder ... The postal addresses and dates of these letters map out an itinerary of the perpetrator(s) ... which single out the perpetrator from the other likely suspects."

Rosenberg also says three senior U.S. biodefense officials have given the same name of a likely suspect to the FBI. She would not reveal that person's name, but said he is a former USAMRIID scientist, who she understands is working for a defense or CIA contractor in the Washington metropolitan area. Rosenberg says that the FBI has questioned the individual, along with many other former biodefense scientists.

Interestingly, William C. Patrick III, the founder of the U.S. military's biological weapons program, and the man who taught the folks at the Army's Dugway Proving Grounds in Utah how to make dry anthrax (using a harmless anthrax substitute, though), is no longer willing to talk to the press. Contacted by Salon Thursday, Patrick said that he has been misquoted in the media, and doesn't wish to comment on the investigation anymore. Rosenberg believes that the anthrax perpetrator may know Patrick, because the attack resembles a classified study that Patrick wrote for a CIA contractor a couple of years ago, which tried to predict how an anthrax attack through the mail would work.

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